I started 100 mg of oral progesterone a little over a week ago, and I haven’t had a good nights sleep in at least 5 days. I wake up between 2 and 4 in the morning, usually within a half hour of 3. Sometimes from a nightmare, which I never used to have until I realized I was trans, sometimes I’m just awake. Last night I didn’t sleep at all so far as I can tell. I see most people saying it does the oppositw for them, just knocks them right out in underan hour, but I definitely don’t get that. I really don’t want the cause of my inability to sleep to be the prog because I’ve already noticed my boobs feel bigger, but has anyone else had this experience?


Nightmares and strange dreams are actually commonly reported on oral progesterone. The prog is metabolized into other hormones that have a wide variety of mental effects, including feeling giddy when awake and such.
In my and other people that I know’s experiences, oral can feel like a slight alcohol buzz or outright drunk. Rectal was/is completely different.
oh, interesting - yeah, maybe it’s the secondary metabolites 🤷♀️ still, I haven’t heard of insomnia as a side effect before (not that this means much, it could still be a known side effect - I just can’t find it mentioned anywhere)