• HonoraryMancunian@lemmy.world
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    11 months ago

    Matt Le Blanc:

    "…I guess you’re keeping the 20 bucks you owe me.”

    This is exactly the kind of humour Perry would’ve appreciated

  • fosforus@sopuli.xyz
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    11 months ago

    And Elon Musk eats that stuff for breakfast and keeps truckin’ on. Life is unfair.

    • NoSpiritAnimal@lemmy.world
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      11 months ago

      He is not just truckin’ along. The man looks like someone’s aunt is trying to build mass. He looks like an uncooked weisswurst got a planet fitness membership. He is a torso made manifest. Hair plugs and ozempic riding the right-wing-pipeline down a k-hole.

    • sharpiemarker@feddit.de
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      11 months ago

      Hot tubs + drugs don’t mix. Even alcohol is dangerous because the effect of the hot tub increases the effects. We bought a hot tub recently and they’re are dozens of warnings about drugs/alcohol.

      My recommendation to Elon would be to have a nice big dose and take a long dip.

  • spiderkle@lemmy.ca
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    11 months ago

    Takes note: Don’t do horse-tranquilizers alone in a bath, check. As a matter of fact don’t do any analgesic/anesthetic with additional drugs in a bath, also check.

    • RocketBoots@programming.dev
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      11 months ago

      Calling them horse tranquilizers is misleading. Ketamine was and still is used in medicine and is on the WHO list of essential medicines.

      My cat is prescribed gabapentin. Some even get tramadol. Warfarin literally was rat poison until we got all but the craziest SOBs with an abundance of vitamin K in they’re veins.

      • Hadriscus@lemm.ee
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        11 months ago

        oh, I tried that last month ! Pretty sweet high, relaxing. Like a really soft mdma (really soft!)

        • EatATaco@lemm.ee
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          11 months ago

          If I say I’m serving cat food for dinner, and then whip out a nice piece of salmon sashimi, I wasn’t being misleading because cats eat fish? If so, you’re really killing some of my dad jokes here.

        • prole@sh.itjust.works
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          11 months ago

          It’s also used on infants for anesthesia due to how safe it is.

          Maybe we should start calling it “baby tranquilizer” instead?

  • saze@feddit.uk
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    11 months ago

    Damn, I did not know Ket could depress respiration like this! In fact Ket is used medicinally in place of opioids as it doesn’t depress respiration. But here is the TIL part: it should not be mixed with benzos or alcohol (or other depressants I would imagine). I don’t use bu I hope someone who does get to read this.

    • 14th_cylon@lemm.ee
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      11 months ago

      ketamine is anaesthetic and was used in the past in combat medicine and such, because it is quite safe when administered by untrained staff. the fact it is used to treat depression is new to me, but getting in the pool while high on it is the most stupid idea ever :(.

    • prole@sh.itjust.works
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      11 months ago

      He was in the bathtub and drowned. If you take enough ketamine, it will literally incapacitate you (for many, that’s the entire point). He did this in a bathtub.

      He did not die from overdosing on ketamine, because that’s nearly impossible. He was stupid and incapacitated himself in a bathtub and drowned. It sucks, and it’s easy to just blame a chemical.

      I’m sure there are people who die after having a couple drinks and getting into the tub, but do we then say that they “died due to the acute effects of alcohol”? No. We say they drowned.

  • IDontHavePantsOn@lemm.ee
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    11 months ago

    Im fairly certain that what I’m about to say will be disliked by ketamine users and abstainers.

    Ketamine is garbage at everything besides temporarily lobotomizing people. It works for it’s many uses because it makes the user stupid. It’s often given to suicidal people, not because it’s a miracle drug, but because it incapacitates them in a safe manner.

    That said, it’s great at making people too stupid to be able to hurt themselves, most of the time. It’s great at numbing psychological pain because the user will be too stupid to conceptualize their own thoughts or realize where they are physically.

    It’s also hard on the urinary system and has a fleeting high.

    If you like ketamine then by all means, you do you. If you may be interested in trying ketamine, become a zombie safely, just don’t expect it to cure your depression, woes, or any of your other problems.

    • StorminNorman@lemmy.world
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      11 months ago

      Yeah, I’m gonna take the peer reviewed studies results that show that ketamine is quite effective with relieving drug resistant depression over this post of yours…

      • madcaesar@lemmy.world
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        11 months ago

        I have no dog in this fight, but any studies done on brain chemistry and psychological effects need to be taken with a grain of salt. We know so little about the brain and consciousness that most of the stuff we’re trying and doing are educated guesses.

      • dangblingus@lemmy.dbzer0.com
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        11 months ago

        But your assessment of its efficacy is not contradictory to DontHavePants observation. They didn’t say it wasn’t effective.

        • StorminNorman@lemmy.world
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          11 months ago

          Ketamine is garbage at everything besides temporarily lobotomizing people. It works for it’s many uses because it makes the user stupid. It’s often given to suicidal people, not because it’s a miracle drug, but because it incapacitates them in a safe manner.

          This quote from you contradicts what you’ve just said.

          • IDontHavePantsOn@lemm.ee
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            11 months ago

            It doesn’t. I can speak to it’s mode of action without speaking to it’s reason of use or efficacy. It’s highly effective. It’s great at what it’s used for. It also temporarily makes the user stupid and incapacitates them.

            • Metacortechs@lemmy.world
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              11 months ago

              That isn’t it’s mode of action, at all.

              It also doesn’t make you stupid, it is a disassociative anesthetic so you lose touch, to varying degrees, of your senses. At high enough doses even your sense of hearing becomes strange and I would bet if my doc gave me more it would fail almost completely. That’s not a place I want to go however.

              Despite that, and appearing to be incapable of coordinated movement or speech, the mind is still active. Altered, yes. But active and intact. I am always aware of my partner in the room/bed with me, the dog checking things out, I just choose not to interact with them to continue exploring memories, or alien landscapes, or just turn off my mind, listen to the music, and let the drug work while the most fantastic and surreal images come and go.

              I’m here today because of ketamine. Disinformation and pearl clutching threatens to reduce access to it, and could cost lives, speaking only of this one niche use.

              • IDontHavePantsOn@lemm.ee
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                11 months ago

                I’ve ingested a ton of ketamine myself, so theres no pearl clutching here. I’ll be back tomorrow to continue arguing semantics.

                • prole@sh.itjust.works
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                  11 months ago

                  So you sound like someone with some experience using drugs (particularly those of psychedelic or hallucinatory nature), right?

                  So you would know that drugs effect everyone differently. Personally, I never abused ketamine, but I have k-holed a handful of times, and my personal experience was that it had a profound effect on me in many ways.

                  But that’s just my personal experience. Nothing more, nothing less.

                  Anyway, those who know, know MXE (methoxetamine) was way better for that brief period of time before the supply permanently dried up.

            • StorminNorman@lemmy.world
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              11 months ago

              You didn’t though. You used a blanket statement. As evidenced by your use of the word “everything”. Your entire initial comment reads as if it was written in the grip of anti drugs hysteria in the 1950s and shows none of the nuance you’re now trying to claim it does.

              You’re also wrong on its mode of action, so you’re not even speaking to that. It doesn’t work by making the user “too stupid to conceptualize their own thoughts or realize where they are physically”.

              • chitak166@lemmy.world
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                11 months ago

                He said everything except “temporarily lobotomizing people” which was clearly hyperbole.

                He then gave examples where the sedation provided by ketamine can be beneficial.

    • ImFresh3x@sh.itjust.works
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      11 months ago

      I judge my desire to try drugs by how people act when they’re on them. Do they look like they’re having fun at least? Two drugs I’ve never had an interest in:

      Ketamine

      Nitrous

    • butterflyattack@lemmy.world
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      11 months ago

      I would add to this that anyone doing ketamine should not do it in the bath, which seems to be what happened here. The same happened to someone I knew, she drowned in the tub.

      • driving_crooner@lemmy.eco.br
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        11 months ago

        Any drug close water where you can drown is a recipe for disaster. Someone I knew pop and acid tab at the beach and drown itself.

      • prole@sh.itjust.works
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        11 months ago

        Yeah, “don’t k-hole in the bathtub” seems like pretty good (and hopefully obvious) advice. This seems more like user error than the acute effects of the drug itself.

        He didn’t die from overdosing on ketamine, because that’s nearly impossible.

        He drowned.

    • prole@sh.itjust.works
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      11 months ago

      Or, get this, everyone experiences drugs differently and your bad anecdote is irrelevant next to the mountains of evidence and peer reviewed studies.

    • chitak166@lemmy.world
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      11 months ago

      Ketamine is definitely up there with ‘hip’ drugs not worth trying.

      Along with MDMA and Xanax.

      I don’t really respect anyone who does these because they’re usually living a lifestyle that leads to nowhere.

      • Hadriscus@lemm.ee
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        11 months ago

        Hmmm, I don’t know the second one but mdma is great fun. Of course you have to be in a good state of mind before trying, but it’s a potent empathogen that has its uses.

        • EatATaco@lemm.ee
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          11 months ago

          One of the most fun nights of my life is when I went to visit a friend at his university, we took some and he immediately ended up with some girl and disappeared on me.

          So I decided that I would just wander his campus looking for parties. I took shots with frat boys, danced with some gays guy out dressed in drag, played chess with some guy on the quad (he would have destroyed me even if I was sober), found another friend and went and partied with her and her lesbian friends (“wait you’re a lesbian now?” “Maybe not sure”) and then made the biggest mistake of my life when I turned down joining them when I was making a hasty exit after I noticed one of the girls was eating the other out right next to me on the couch.

          • Hadriscus@lemm.ee
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            11 months ago

            wild 😁 Yea I get how you’d want a do over heheh

            My experience is very vanilla coming after yours, but we had some of that and spent the entire night in my last floor apartment just chatting and drinking looking at the sea. It was full moon too. At one point I must have thought it was around midnight, I peeked at the east-facing window in my room and a big ball of fire was burning on the horizon. Time really flew this night…

      • prole@sh.itjust.works
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        11 months ago

        You’d be shocked by how many very successful and incredibly intelligent people have used drugs (including MDMA). Many still use them regularly. MDMA, in the right setting and in moderation, can (will) be a life-affirming and beautiful experience.

        This honestly sounds like something a child would say after having D.A.R.E. in elementary school.

          • pineapple_pizza@lemmy.dexlit.xyz
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            11 months ago

            I know people like this. Though I should probably define regularly as once every few weeks for k. Probably closer to like 2 to 4 times a year for MDMA. Obviously if you’re doing stuff every day then you won’t be productive in a job

      • smooth_tea@lemmy.world
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        11 months ago

        MDMA not worth it? It’s euphoria and love in a pill, not addictive, and quite safe when you do not abuse it. Millions of people use it and have been using it for about half a century and the vast majority of it restricts it to when they’re partying with few side effects. I think you misjudge its use a bit.

        Yes it can be acutely abused because you’re chasing the dragon on nights that you do use it, but that is also a result of its illegal nature and a lack of education.

        Of the chemical variants of drugs, I’d say it’s probably one of the few that is actually worth it, besides LSD.

  • lingh0e@sh.itjust.works
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    11 months ago

    Ketamine’s effects on respiratory shit is serious.

    I almost stopped breathing during an assisted experience because I didn’t realize mixing K with benzos was dangerous.

    • intensely_human@lemm.ee
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      11 months ago

      It’s how Elijah McClain died too. Young kid stopped by police for matching the description. They shot him full of ketamine and he died of respiratory failure.

      • takingbacksunday@lemmy.world
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        11 months ago

        Can’t recall all the details, but the impression I got was his respiratory failure was caused by the officer choking him with a knee on his windpipe. EMTs did give a very high dose of ketamine at 5mg/kg body weight, whereas I usually use 0.5-1mg/kg body weight to put patients under surgical anesthesia.

  • Rob T Firefly@lemmy.world
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    11 months ago

    When Friends was current I wasn’t a fan, the small bits I’d seen mostly annoyed me and - disaffected gothy teens/early twenties guy that I was - I dismissed it as one of those things everyone in the mainstream liked and was therefore obviously garbage.

    Nowadays I’m married to a Friends fan who is now showing me the series. As we progress through the box set I’m realizing it’s actually pretty good, a couple of the characters actually still annoy me when they’re focused on but there’s a ton else going on that’s pretty entertaining. I’m particularly surprised to be enjoying Chandler so much.

    • Underwaterbob@lemm.ee
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      11 months ago

      I’m still not sure I’d call it good, but it was a big step up from sitcoms before it. It tried pretty hard to not be sexist, and introduced some diversity that wasn’t just John Ritter pretending to be gay for lulz. It is still spectacularly unrealistic, but whatever. It’s a sitcom! It does have some genuinely funny moments.

      I still periodically get “Smelly Cat” stuck in my head. Fuck, I’m guilty of making Ross-esque synthesizer music…

      • Rob T Firefly@lemmy.world
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        11 months ago

        Very true,. There are also definitely still some 1990s-era LGBTQIA+ phobic jokes which were wrong then and really stick out now, but in general I’d call the writing surprisingly decent.

        As a New Yorker, though, I still couldn’t afford that apartment in a million years.

  • dangblingus@lemmy.dbzer0.com
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    11 months ago

    Cue all of the commenters saying how amazing unprescribed unmonitored narcotic abuse is great for their mental health.

  • computerscientistI@lemm.ee
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    11 months ago

    I had no idea about what ketamine actually is, It seemms most likely to me that it was administered via IV by a MD, no? Wasn’t this manslaughter by the doctor, then?

    • Agent641@lemmy.world
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      11 months ago

      Ketamine can be taken as pills, liquid ingested, snorted, injected (self administered), or up the bum.

      You dont have to do all these at the same time unless youre trying to be the heavyweight world champion of K-holeing

    • Flying Squid@lemmy.world
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      11 months ago

      If only there were some world-wide interconnected network of computers full of more information than you could possibly imagine, all of it searchable instantly where you could find out who Matthew Perry was.

      Alas…

      • Evil_Shrubbery@lemm.ee
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        11 months ago

        I remember the world pre-pocket (or home) internet. We thought access to information was the core issue of people being ignorant/misinformed/stupid, surely instant access to world libraries with all the cumulated human knowledge would alleviate that.

        We were wrong.

    • CoggyMcFee@lemmy.world
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      11 months ago

      You do realize you have the option not to reply to posts that aren’t relevant to you, right?

      • chitak166@lemmy.world
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        11 months ago

        Yeah, but why should we care about this guy when people die from drugs all the time?

            • CoggyMcFee@lemmy.world
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              11 months ago

              Because you wrote to me directly, as opposed to the person that posted the article. Also, it’s entertaining me that you’re desperately hoping someone says what he’s well known for so you can say you don’t waste your time with pop culture garbage

              • chitak166@lemmy.world
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                11 months ago

                Lol, nice projection.

                I’m guessing you like this guy and get mad when someone doesn’t know who he is.

    • namelessdread@lemmy.world
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      11 months ago

      Disregarding all the other stuff, the reports say he was being treated with ketamine for anxiety and depression. He had decades of mental health struggles.

      No matter who the person is, he was still a person.

  • ForestOrca@kbin.social
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    11 months ago

    From wikipedia: “On December 15, 2023, Perry’s death was revealed to have occurred due to “acute effects of ketamine”.[94][95] Other circumstances that contributed to his death included the effects of buprenorphine, drowning, and coronary artery disease.[94]”
    https://en.wikipedia.org/wiki/Matthew_Perry#Death
    I was all, “who’s Matthew Perry”?