• SuperNovaStar@lemmy.blahaj.zoneEnglish
    4·
    1 day ago

    Well if it was measurable in mg, that would be super bad, since oral estrogen doses for trans women are like 2-4 mg per day. For it to be consumed by men regularly with no feminizing effects, I think it would need to be at least in the picograms/gallon range.

    … but then again, i’m not a doctor. I could be wrong about that.

    Edit: Turns out it’s more than I was expecting. Maybe if you are taking an anti-androgen you might get a noticeable amount of E in your system if you drink multiple liters of milk per day? Not that i’d recommend it, but it is interesting.

    • homura1650@lemmy.world
      3·
      1 day ago

      The reference levels of estrodial for males is 10-50 pg/mL.

      4mg daily of oral estrodial got me from (presumably) that range to around 95 pg/mL. Let’s round this to an estimate of a 50 pg/mL, or an increase of 12.5 pg/mL per mg of oral estrodial.

      A gallon of milk, would have 0.000492mg of estrodial, which would translate to a 0.00615 pg/mL increase. That is about 0.0015% the reference range for cis men.

      Interestingly, high testosterone levels actually increase men’s estrogen levels, as testosterone gets metabolized into estrogen.

      https://emedicine.medscape.com/article/2089003-overview?form=fpf#a1