I’m a huge fan, Rincewind is one of my fav characters. I think they can just be read in publishing order, whilst characters and some plot lines do crossover each book is a story on its own.

Colour of Magic is a perfect starting point imho.

In the Discworld series there are some parodied Australian wizards in The Last Continent book.

Perhaps there’s an argument against scientific hubris: if we look through history, and to this day, we can see those who champion rigid adherence to religion above all else as the cause of much suffering. On the other hand the latter half of the 10 Commandments provide a fairly sensible groundwork for law and order in society.

As for love, whilst we may not be able to measure it directly, we can certainly see evidence of it’s power; “I would do anything for love, I’d run right in to hell and back” Meatloaf. I’d also argue that the core human emotions can be explained by evolution, and compared with animal behaviour. In preparing for fight or flight fear can be measured in a raised heart rate, the release of chemicals, and electrical activity within the brain.

I think one of the cornerstones of science is that it is open to a theory being overturned as new evidence comes to light.

Duhem–Quine, or the "veil of perception”, well yes, we do have to make some assumptions somewhere, you assume that I know how to read and understand your words written in English, which I do and I’m sure a great many others do - perhaps we could use this as a baseline example of knowledge. We all know the word “stop” and it’s meaning in context though we might not all react to it in the same way.

Then again, it could all just be my imagination.

Are you suggesting there may be forces or powers we can’t yet measure?

Because that’s pretty much what science has been about for all of human evolution. We’ve observed events, and then tried to work out why they happen, and yet in all that time we’ve been unable to prove, or disprove god.

We can think practically about knowledge too.

I put my hand on a hot stove, it burns, I remove my hand and the burning stops. Isn’t that knowledge?

I have a hypothesis, I collect evidence, record the results and see if it supports the hypotheses.

The experiment is repetable.

https://en.m.wikipedia.org/wiki/Scientific_method